Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887129 | 0.94 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL14529462 | 0.90 | CYP1A2 (0.44) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL1431372 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL8908261 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6413852 | 0.82 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL11082542 | 0.82 | STAT3 (0.51) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL4175922 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL11854230 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL30542740 | 0.76 | STAT3 (0.49) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL9749766 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | GLAXO GROUP LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | MRPL21, MRPS18A, MRPL19 | KDM4E 4136/4885ALDH1A1 3772/4885HPGD 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.