Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713816 | 0.88 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL703425 | 0.88 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL703091 | 0.83 | TSHR (0.33) | ESR1ESR2 | |
| SCHEMBL4271660 | 0.82 | SLC9A1 (0.32) | SLC9A1KCNA3 | |
| SCHEMBL436840 | 0.80 | TSHR (0.36) | ESR1ESR2 | |
| SCHEMBL3230668 | 0.79 | KDM4E (0.33) | SLC9A1KCNA3 | |
| SCHEMBL8908096 | 0.78 | ESR1 (0.33) | SLC9A1ESR1ESR2 | |
| SCHEMBL12814698 | 0.77 | KCNH2 (0.42) | — | |
| SCHEMBL18108184 | 0.77 | KCNH2 (0.42) | — | |
| SCHEMBL1314568 | 0.77 | KCNH2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624680-A | SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0710688-A1 | HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-05-08 | — | — | EP | disclosed |