Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.41 |
| ▸ | RARG | P13631 | 12/20 | 0.41 |
| ▸ | RARA | P10276 | 8/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737708 | 0.81 | RARB (0.46) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8772692 | 0.80 | RARB (0.45) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8908324 | 0.79 | RARB (0.41) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7642401 | 0.78 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6426143 | 0.76 | RARB (0.46) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7640559 | 0.76 | RARB (0.44) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL4517661 | 0.74 | RARB (0.39) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL5736992 | 0.73 | RXRA (0.47) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8772690 | 0.71 | RARB (0.45) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL5736491 | 0.70 | RARB (0.43) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618931-A | SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | ALLERGAN | 1997-04-08 | — | — | US | disclosed |