Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906657 | 0.90 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL708796 | 0.89 | TSHR (0.38) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL17966582 | 0.89 | TSHR (0.38) | TSHRTDP1ALDH1A1 | |
| SCHEMBL10919178 | 0.86 | TSHR (0.35) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL3481719 | 0.83 | TSHR (0.33) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL2594254 | 0.83 | TSHR (0.39) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL10942763 | 0.81 | — | — | |
| SCHEMBL30843344 | 0.81 | TSHR (0.53) | TSHRTDP1ALDH1A1FAAHLMNA | |
| SCHEMBL7522756 | 0.81 | TSHR (0.44) | TSHRALDH1A1LMNA | |
| SCHEMBL8908645 | 0.81 | TSHR (0.53) | TSHRTDP1ALDH1A1FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624680-A | SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0710688-A1 | HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-05-08 | — | — | EP | disclosed |