Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL8908381

CCOCC.COC.OCCO.OCCOCCOCCOCCO

nearest known ligand 0.65

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
TSHR P16473 3/20 0.53
MAPK1 P28482 2/20 0.53
THRB P10828 2/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 1/20 0.50
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLCO1B3 Q9NPD5 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
APP P05067 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL6329241 0.97 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATSHRMAPK1
Tetraethylene Glycol SCHEMBL7114296 0.97 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATSHRMAPK1
Ethylene Glycol SCHEMBL5776639 0.95 ALDH1A1 (0.74) ALDH1A1MEN1KMT2ATSHRMAPK1
Tetraethylene Glycol SCHEMBL23931240 0.95 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ATSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL4138266 0.95 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ATSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL6329214 0.95 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL28205410 0.95 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL21811316 0.92 ALDH1A1 (0.62) ALDH1A1MEN1KMT2ATSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL4512440 0.92 ALDH1A1 (0.78) ALDH1A1MEN1KMT2ATSHRMAPK1
Diethylene Glycol Monoethyl Ether SCHEMBL3259182 0.92 ALDH1A1 (0.78) ALDH1A1MEN1KMT2ATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0647245-B1 POLYMERS OF HALOPERFLUORO AND PERFLUORO ETHERS DOW CHEMICAL CO (US) 1997-11-12 EP disclosed
EP-0647245-A1 POLYMERS OF HALOPERFLUORO AND PERFLUORO ETHERS THE DOW CHEMICAL COMPANY (US) 1995-04-12 EP disclosed
US-5393852-A Crosslinkable, melt processability; electrolytic cell mambranes, films THE DOW CHEMICAL COMPANY (US) 1995-02-28 US disclosed
WO-1994000502-A1 POLYMERS OF HALOPERFLUORO AND PERFLUORO ETHERS THE DOW CHEMICAL COMPANY (US) 1994-01-06 WO disclosed
US-5264508-A Membranes and electrolytic cells from trifluorovinyl ether copolymers for fuel cells THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed