Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.64 |
| ▸ | CCR8 | P51685 | 1/20 | 0.64 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30266840 | 1.00 | CCR1 (0.64) | CCR1CCR8METAP2CYP2A6NOS2 | |
| SCHEMBL29419394 | 0.87 | — | — | |
| SCHEMBL5155 | 0.87 | — | — | |
| SCHEMBL3167663 | 0.87 | CCR1 (0.48) | CCR1CCR8NOS2SMN1; SMN2KCNH2 | |
| Bromide SCHEMBL11282133 | 0.85 | CCR1 (0.46) | CCR1CCR8NOS2NOS3SMN1; SMN2 | |
| SCHEMBL9146011 | 0.85 | CCR1 (0.46) | CCR1CCR8NOS2SMN1; SMN2KCNH2 | |
| SCHEMBL14732969 | 0.84 | CCR1 (0.64) | CCR1CCR8METAP2CYP2A6NOS2 | |
| SCHEMBL7952137 | 0.83 | CCR1 (0.70) | CCR1CCR8METAP2CYP2A6NOS2 | |
| SCHEMBL14085152 | 0.82 | CCR1 (0.67) | CCR1CCR8METAP2CYP2A6NOS2 | |
| SCHEMBL10894853 | 0.80 | CCR1 (0.64) | CCR1CCR8METAP2CYP2A6NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601113-B1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE | CIS BIO INT (FR) | 1997-01-08 | — | — | EP | disclosed |
| US-5457184-A | Medical diagnosis | CIS BIO INTERNATIONAL (FR) | 1995-10-10 | — | — | US | disclosed |
| US-5432101-A | Complex consists of biologically active molecule associated by coupling or adsorption with the complex | COMPAGNIE ORIS INDUSTRIE SA (FR) | 1995-07-11 | — | — | US | disclosed |
| EP-0601113-A1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE. | CIS BIO INT (FR) | 1994-06-15 | — | — | EP | disclosed |
| US-5220012-A | Macropolycyclic rare earth complexes and application as fluorescent tracers | COMPAGNIE ORIS INDUSTRIE SA (FR) | 1993-06-15 | — | — | US | disclosed |
| WO-1993005049-A1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE | CIS BIO INTERNATIONAL (FR) | 1993-03-18 | — | — | WO | disclosed |
| US-4927923-A | IMMUNOLOGY | COMPAGNIE ORIS INDUSTRIES (FR) | 1990-05-22 | — | — | US | disclosed |