SCHEMBL8908405

SCHEMBL8908405

CCCNC(=O)CCCC(C)C(=O)N1CCc2ccc(C(F)(F)F)cc21

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
XIAP P98170 1/20 0.44
BIRC2 Q13490 1/20 0.44
CNR2 P34972 1/20 0.42
HTR2A P28223 3/20 0.41
HTR2C P28335 3/20 0.41
NOTUM Q6P988 1/20 0.41
MTTP P55157 1/20 0.38
ATM Q13315 1/20 0.37
HTR2B P41595 2/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 1/20 0.36
ROCK1 Q13464 1/20 0.36
DPP7 Q9UHL4 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
RHOC P08134 1/20 0.36
RHOA P61586 1/20 0.36
NAMPT P43490 1/20 0.35
ACACB O00763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902884 0.73 XIAP (0.54) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL8908402 0.72 CNR2 (0.44) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL30038606 0.69 NOTUM (0.78) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL8893534 0.69 XIAP (0.58) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL8908396 0.69 CNR2 (0.45) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL2530222 0.68 CNR2 (0.62) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL16600192 0.67 CNR2 (0.61) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL23207270 0.66 XIAP (0.58) XIAPBIRC2CNR2HTR2AHTR2C
SCHEMBL12890510 0.65 NOTUM (0.66) CNR2HTR2AHTR2CNOTUMATM
SCHEMBL20988315 0.65 POLB (0.59) NOTUMALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997045408-A1 HERBICIDAL INDOLINES ZENECA LIMITED (GB) 1997-12-04 WO disclosed