Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530222 | 0.86 | CNR2 (0.62) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL30038606 | 0.85 | NOTUM (0.78) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL23207270 | 0.81 | XIAP (0.58) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL8893534 | 0.81 | XIAP (0.58) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL27544652 | 0.78 | CNR2 (0.53) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL9393577 | 0.77 | CNR2 (0.52) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL10241674 | 0.77 | NOTUM (0.66) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL16600474 | 0.76 | NOTUM (0.71) | NOTUMHTR2AHTR2CXIAPBIRC2 | |
| SCHEMBL15544353 | 0.76 | CNR2 (1.00) | CNR2NOTUMHTR2AHTR2CXIAP | |
| SCHEMBL19411099 | 0.76 | CNR2 (0.49) | CNR2NOTUMHTR2AHTR2CXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850203-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| EP-3049405-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-07-28 | — | — | US | disclosed |
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | CNR2 4733/4885NOTUM 2534/4885HTR2A 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.