SCHEMBL890851

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19058451	0.91	BRD4 (0.43)	BRD4GAAKMT2AMALT1BCHE
	SCHEMBL17928510	0.90	BRD4 (0.42)	BRD4GAAKMT2AMALT1BCHE
	SCHEMBL19058464	0.85	NQO2 (0.46)	BRD4MAPTKAT2BNPC1RAB9A
	SCHEMBL10155416	0.84	KMT2A (0.44)	BRD4MAPTNPC1RAB9ALMNA
	SCHEMBL906324	0.84	MAPT (0.42)	BRD4MAPTKAT2BNPC1RAB9A
	SCHEMBL10193104	0.84	NPC1 (0.44)	BRD4MAPTKAT2BNPC1RAB9A
	SCHEMBL891344	0.83	MAPT (0.54)	BRD4MAPTKAT2BNPC1RAB9A
	SCHEMBL19058450	0.83	HCAR3 (0.52)	MAPTNPC1RAB9ALMNAGAA
	SCHEMBL891296	0.82	BRD4 (0.45)	BRD4MALT1BCHEIDO1
	SCHEMBL1062316	0.82	MAPT (0.47)	BRD4MAPTNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.