Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29820981 | 0.80 | KMT2A (0.53) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL9081038 | 0.79 | KMT2A (0.49) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL15132492 | 0.78 | KMT2A (0.54) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL7362002 | 0.76 | KMT2A (0.52) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL17665039 | 0.75 | KMT2A (0.62) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL18982241 | 0.75 | KMT2A (0.49) | KMT2AEPHX2FABP5FABP7CASP3 | |
| Hydrochloric Acid SCHEMBL7357624 | 0.75 | KMT2A (0.51) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL14407142 | 0.74 | KMT2A (0.52) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL30174112 | 0.74 | KMT2A (0.59) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL21661027 | 0.74 | KMT2A (0.50) | KMT2AEPHX2FABP5FABP7CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672605-A | ADMINISTERING TO TREAT AUTOIMMUNE DISORDERS, TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 1997-09-30 | — | — | US | disclosed |
| US-5583139-A | Marcolide immunomodulators | ABBOTT LABORATORIES (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0729471-A1 | SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS | Abbott Laboratories (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5527907-A | IMMUNOSUPPRESSANTS | ABBOTT LABORATORIES (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1995014023-A1 | SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1995-05-26 | — | — | WO | disclosed |