Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.48 |
| ▸ | FABP7 | O15540 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7357624 | 0.98 | KMT2A (0.51) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL8973963 | 0.88 | KMT2A (0.48) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL15132492 | 0.86 | KMT2A (0.54) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL21661027 | 0.85 | KMT2A (0.50) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL19602147 | 0.85 | KMT2A (0.50) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL13411461 | 0.85 | KMT2A (0.50) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL3888794 | 0.83 | KMT2A (0.54) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL17245018 | 0.82 | KMT2A (0.58) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL4839280 | 0.82 | KMT2A (0.52) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL5497604 | 0.82 | KMT2A (0.55) | KMT2AEPHX2FABP5FABP7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018208-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-18 | — | — | US | disclosed |
| US-11732019-B2 | Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-22 | — | — | US | disclosed |
| US-20180127476-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-10 | — | — | US | disclosed |
| US-7501444-B2 | Prenylation inhibitors and methods of their synthesis and use | PPD DISCOVERY, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-20070010561-A1 | PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE | PHARMACEUTICAL PRODUCT DEVELOPMENT, LLC | 2007-01-11 | — | — | US | disclosed |
| US-6025472-A | PEPTIDE ALDEHYDES WHICH ARE POTENT INHIBITORS OF FACTOR XA, USEFUL AS THERAPEUTIC AGENTS FOR DISEASE STATES IN MAMMALS CHARACTERIZED BY ABNORMAL THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| US-5696231-A | ANTICOAGULANTS; CARDIOVASCULAR DISORDERS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0801654-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996019493-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1996-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018208-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | NPY4R, NPY5R, NPY1R | KMT2A 2517/4885EPHX2 2845/4885FABP5 639/4885 |
| US-11732019-B2 | Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors | NPY4R, NPY5R, NPY1R | KMT2A 2517/4885EPHX2 2845/4885FABP5 639/4885 |
| US-20180127476-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | NPY4R, NPY5R, NPY1R | KMT2A 2517/4885EPHX2 2845/4885FABP5 639/4885 |
| US-20070010561-A1 | PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE | FNTA, RCE1, GGPS1 | KMT2A 4201/4885EPHX2 1146/4885FABP5 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.