Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.52 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614765 | 0.99 | FABP4 (0.53) | FABP4TOP1CYCSLMNADHFR | |
| SCHEMBL8909617 | 0.98 | FABP4 (0.52) | FABP4TOP1CYCSLMNADHFR | |
| SCHEMBL8909527 | 0.88 | TOP1 (0.45) | FABP4TOP1CYCS | |
| SCHEMBL8909582 | 0.87 | TOP1 (0.44) | FABP4TOP1CYCS | |
| SCHEMBL8908515 | 0.87 | TOP1 (0.44) | FABP4TOP1CYCS | |
| Hydrochloric Acid SCHEMBL8865595 | 0.86 | TOP1 (0.43) | FABP4TOP1CYCS | |
| Hydrochloric Acid SCHEMBL8865553 | 0.86 | TOP1 (0.43) | FABP4TOP1CYCS | |
| SCHEMBL10730297 | 0.85 | MEN1 (0.57) | TOP1CYCSMEN1KMT2APTPN7 | |
| SCHEMBL29558419 | 0.83 | TOP1 (0.61) | TOP1CYCSMEN1KMT2APDE2A | |
| SCHEMBL3794157 | 0.83 | TOP1 (0.61) | TOP1CYCSMEN1KMT2APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | claimed |