Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.68 |
| ▸ | MERTK | Q12866 | 5/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8896596 | 0.99 | NPY5R (0.67) | NPY5RMERTKMAPK8MAPK9APP | |
| Hydrochloric Acid SCHEMBL8896597 | 0.99 | NPY5R (0.67) | NPY5RMERTKMAPK8MAPK9APP | |
| SCHEMBL8891157 | 0.83 | NPY5R (0.54) | NPY5R | |
| SCHEMBL8900891 | 0.83 | NPY5R (0.53) | NPY5RAPPBCHEACHE | |
| SCHEMBL13793553 | 0.83 | NPY5R (0.49) | NPY5RAPPBCHEACHE | |
| Hydrochloric Acid SCHEMBL6039631 | 0.83 | NPY5R (0.74) | NPY5RMERTKMAPK8MAPK9APP | |
| Hydrochloric Acid SCHEMBL6039450 | 0.83 | NPY5R (0.74) | NPY5RMERTKMAPK8MAPK9APP | |
| Hydrochloric Acid SCHEMBL8901970 | 0.82 | NPY5R (0.53) | NPY5RAPPBCHEACHE | |
| SCHEMBL8893953 | 0.81 | NPY5R (0.49) | NPY5RMERTK | |
| SCHEMBL8899277 | 0.81 | NPY5R (1.00) | NPY5RMERTKAPPBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |