Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 2/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891058 | 0.85 | NPY5R (0.41) | NPY5RSLC2A1 | |
| Hydrochloric Acid SCHEMBL8901427 | 0.84 | NPC1 (0.43) | NPY5RSLC2A1 | |
| SCHEMBL8893962 | 0.83 | NPY5R (0.50) | NPY5RSLC2A1MERTKCFDPDE5A | |
| SCHEMBL8908620 | 0.81 | NPY5R (0.68) | NPY5RMERTK | |
| Hydrochloric Acid SCHEMBL8896596 | 0.81 | NPY5R (0.67) | NPY5RMERTK | |
| Hydrochloric Acid SCHEMBL8896597 | 0.81 | NPY5R (0.67) | NPY5RMERTK | |
| SCHEMBL8891157 | 0.79 | NPY5R (0.54) | NPY5R | |
| SCHEMBL8891478 | 0.73 | VCP (0.49) | — | |
| SCHEMBL8892788 | 0.73 | NPY5R (0.62) | NPY5R | |
| Hydrochloric Acid SCHEMBL8898939 | 0.72 | VCP (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |