Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536907 | 0.87 | SIGMAR1 (0.63) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL31127843 | 0.87 | SIGMAR1 (0.63) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL2794487 | 0.84 | SIGMAR1 (0.59) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL2454752 | 0.84 | SIGMAR1 (0.59) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL2794958 | 0.84 | SIGMAR1 (0.59) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL19868618 | 0.83 | SIGMAR1 (0.58) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL11872517 | 0.83 | SIGMAR1 (0.58) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL27919164 | 0.83 | SIGMAR1 (0.58) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL667265 | 0.83 | SIGMAR1 (0.58) | SIGMAR1BCHEGAAATMPOLB | |
| SCHEMBL666714 | 0.83 | SIGMAR1 (0.58) | SIGMAR1BCHEGAAATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |