Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910484 | 0.77 | IDO1 (0.33) | IDO1 | |
| SCHEMBL7868751 | 0.76 | CA14 (0.35) | EPHX1NPY5R | |
| SCHEMBL7871566 | 0.75 | CA14 (0.35) | IDO1CNR1CNR2 | |
| SCHEMBL7872292 | 0.72 | EPHX1 (0.37) | EPHX1NPY5RIDO1CNR1CNR2 | |
| SCHEMBL7875500 | 0.63 | CA14 (0.35) | EPHX1NPY5RIDO1CNR1CNR2 | |
| SCHEMBL7863583 | 0.62 | CA14 (0.36) | EPHX1NPY5RIDO1CNR1CNR2 | |
| SCHEMBL7871683 | 0.62 | EPHX1 (0.40) | EPHX1NPY5RIDO1CNR1CNR2 | |
| SCHEMBL21578136 | 0.61 | KDM4A (0.42) | — | |
| SCHEMBL7870267 | 0.61 | NPY5R (0.39) | EPHX1NPY5RALDH1A1IDO1CNR1 | |
| SCHEMBL7875564 | 0.61 | EPHX1 (0.39) | EPHX1NPY5RIDO1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771319-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996002542-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |