Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908698 | 0.77 | EPHX1 (0.32) | IDO1 | |
| SCHEMBL7875570 | 0.76 | SSTR4 (0.36) | IDO1EGLN1 | |
| SCHEMBL7872248 | 0.68 | CA14 (0.34) | IDO1 | |
| SCHEMBL7868760 | 0.66 | CA14 (0.34) | IDO1EGLN1 | |
| SCHEMBL7870117 | 0.66 | CA14 (0.33) | IDO1EGLN1 | |
| SCHEMBL7871615 | 0.65 | CA14 (0.33) | IDO1 | |
| SCHEMBL7863559 | 0.62 | SSTR4 (0.37) | IDO1EGLN1 | |
| SCHEMBL7871574 | 0.62 | IDO1 (0.31) | IDO1EGLN1MEN1HTTKMT2A | |
| SCHEMBL7863583 | 0.61 | CA14 (0.36) | IDO1EGLN1 | |
| SCHEMBL7875500 | 0.61 | CA14 (0.35) | IDO1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771319-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996002542-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |