Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.85 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.85 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.85 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907601 | 1.00 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL18290254 | 0.92 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15929304 | 0.92 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197367 | 0.92 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL22390094 | 0.92 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL21779535 | 0.85 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL20962990 | 0.85 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15923360 | 0.85 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL8908387 | 0.85 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL10527664 | 0.85 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |