Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804038 | 1.00 | CASR (0.61) | CASRSMN1; SMN2CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL5268653 | 0.88 | BCHE (0.57) | CASRMEN1KMT2APOLB | |
| SCHEMBL11881252 | 0.84 | SMN1; SMN2 (0.70) | CASRSMN1; SMN2CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL5269238 | 0.84 | MEN1 (0.60) | CASRMEN1KMT2A | |
| SCHEMBL3678776 | 0.83 | SMN1; SMN2 (0.61) | CASRSMN1; SMN2MEN1CYP1A2KMT2A | |
| SCHEMBL3678774 | 0.83 | SMN1; SMN2 (0.61) | CASRSMN1; SMN2MEN1CYP1A2KMT2A | |
| SCHEMBL11877401 | 0.82 | CASR (0.73) | CASRSMN1; SMN2CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL9522067 | 0.81 | SIGMAR1 (0.64) | SMN1; SMN2CYP2D6CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL23330352 | 0.81 | CYP2D6 (0.54) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL79765 | 0.80 | SMN1; SMN2 (0.76) | CASRSMN1; SMN2CYP2D6CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161863-B2 | Chiral catalyst and method for asymmetric reduction of an imine | DALHOUSIE UNIVERSITY (CA) | 2021-11-02 | — | — | US | disclosed |
| US-20200255463-A1 | CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE | DALHOUSIE UNIVERSITY (CA) | 2020-08-13 | — | — | US | disclosed |
| US-5686616-A | Process for preparing an optically active amine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255463-A1 | CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE | C1R, C5, C1S | CASR 4756/4885SMN1; SMN2 3219/4885CYP2D6 53/4885 |
| US-11161863-B2 | Chiral catalyst and method for asymmetric reduction of an imine | C1R, C5, C1S | CASR 4756/4885SMN1; SMN2 3219/4885CYP2D6 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.