Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536365 | 0.85 | EPHX2 (0.41) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL27888454 | 0.84 | EPHX2 (0.46) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL27888506 | 0.83 | EPHX2 (0.43) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL27888535 | 0.83 | EPHX2 (0.43) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL7074067 | 0.83 | NPC1 (0.47) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL1291849 | 0.83 | NPC1 (0.47) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL11233022 | 0.83 | NPC1 (0.47) | EPHX2LIPGNPC1ALDH1A1TSHR | |
| SCHEMBL15128946 | 0.81 | EPHX2 (0.35) | EPHX2LIPGNPC1 | |
| SCHEMBL15128945 | 0.81 | EPHX2 (0.35) | EPHX2LIPGNPC1 | |
| SCHEMBL384203 | 0.80 | NPC1 (0.34) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | disclosed |