Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 1.00 |
| ▸ | MAOB | P27338 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099623 | 1.00 | MAOA (1.00) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL8909768 | 0.98 | MAOA (0.96) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL26648827 | 0.84 | MAOA (0.71) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL5745454 | 0.83 | MAOA (0.70) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL94583 | 0.81 | MAOA (0.68) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL7529147 | 0.81 | MAOA (0.68) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL14490649 | 0.81 | MAOA (0.68) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| Fluoride SCHEMBL1336700 | 0.81 | MAOA (0.68) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL7975244 | 0.80 | MAOA (0.68) | MAOAMAOBSLC6A4SLC6A2SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL7238685 | 0.79 | MAOA (0.65) | MAOAMAOBSLC6A4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4205767-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | Shanghai Senhui Medicine Co., Ltd. (CN) | 2023-07-05 | — | — | EP | disclosed |
| US-11370807-B2 | Process for preparing sulfonamide compounds | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2022-06-28 | — | — | US | disclosed |
| US-20220009952-A1 | PROCESS FOR PREPARING SULFONAMIDE COMPOUNDS | ASCENTAGE PHARMA GROUP CORP LIMITED (CN) | 2022-01-13 | — | — | US | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370807-B2 | Process for preparing sulfonamide compounds | BCL2, BCL3, BAX | MAOA 4050/4885MAOB 3994/4885SLC6A4 2497/4885 |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | MAOA 4689/4885MAOB 4242/4885SLC6A4 4141/4885 |
| US-20220009952-A1 | PROCESS FOR PREPARING SULFONAMIDE COMPOUNDS | BCL2, BCL3, BAX | MAOA 4050/4885MAOB 3994/4885SLC6A4 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.