Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660432 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL15732464 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL225133 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL3023363 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL1392683 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL11624897 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL7548545 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL15655990 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL11425731 | 1.00 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL1469809 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255499-A1 | NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR | 学校法人京都薬科大学 | 2022-12-08 | — | — | WO | disclosed |
| CN-104854145-A | PROCESS FOR PRODUCING A ZIEGLER NATTA PROCATALYST FOR ETHYLENE POLYMERISATION | BOREALIS AG | 2015-08-19 | — | — | CN | disclosed |
| US-5693255-A | AMPHIPHILE AND SURFACTANT WHICH CAN FORM A GEL | SHISEIDO CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |