Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8909156

CCCSc1ccccc1.N

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
MAPK1 P28482 2/20 0.67
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
CYP1A2 P05177 3/20 0.45
CYP2D6 P10635 3/20 0.45
CYP2C19 P33261 3/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 1/20 0.45
HIF1A Q16665 1/20 0.45
FFAR1 O14842 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8909773 0.98 ALDH1A1 (0.64) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL575835 0.97 ALDH1A1 (0.70) ALDH1A1MAPK1CA12CA1CA2
Fluoride SCHEMBL945618 0.95 ALDH1A1 (0.67) ALDH1A1MAPK1CA12CA1CA2
Fluoride SCHEMBL27856295 0.95 ALDH1A1 (0.67) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL28010061 0.95 ALDH1A1 (0.67) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL23289811 0.89 ALDH1A1 (0.58) ALDH1A1MAPK1CA12CA1CA2
Ammonia Solution, Strong SCHEMBL19133464 0.86 ALDH1A1 (0.61) ALDH1A1MAPK1MAOAMAOBMTNR1A
SCHEMBL12432111 0.84 ALDH1A1 (0.52) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL13397872 0.84 CA12 (0.61) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL4179998 0.83 ALDH1A1 (0.64) ALDH1A1MAPK1MAOAMAOBMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436949-B Tetradentate ligand, metal complex, and preparation methods and applications thereof 上海巽田科技股份有限公司 2023-09-22 CN disclosed
CN-114436949-A Tetradentate ligand and metal complex, and preparation method and application thereof 上海巽田科技股份有限公司 2022-05-06 CN disclosed
US-5672588-A Purine derivatives NOVO NORDISK A/S (DK) 1997-09-30 US disclosed
EP-0603348-A1 PURINE DERIVATIVES NOVO NORDISK A/S (DK) 1994-06-29 EP disclosed
WO-1993023418-A1 PURINE DERIVATIVES NOVO NORDISK A/S (DK) 1993-11-25 WO disclosed