Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994014 | 0.84 | PTGER4 (0.64) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL6894550 | 0.81 | KEAP1 (0.46) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL6053663 | 0.78 | PTGER4 (0.81) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL1261128 | 0.77 | PTGER4 (0.77) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL31212507 | 0.77 | PTGER4 (0.77) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL29174155 | 0.76 | CD274 (0.64) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL9357793 | 0.75 | PTGER1 (0.53) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL4979854 | 0.73 | PTGER4 (0.62) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL1904775 | 0.73 | PTGER4 (0.62) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8479912 | 0.72 | PTGER4 (0.70) | PTGER4PTGER3PTGER1PTGER2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670531-A | ENKEPHALINASE OR ANGIOTENSIN CONVERTING ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-09-23 | — | — | US | disclosed |