Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752766 | 0.86 | MEN1 (0.59) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8981259 | 0.84 | MEN1 (0.55) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8442319 | 0.83 | KMT2A (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1150931 | 0.83 | CTSS (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1150932 | 0.83 | CTSS (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5970504 | 0.83 | CTSS (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8442388 | 0.83 | KMT2A (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8282485 | 0.83 | MEN1 (0.58) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3645520 | 0.82 | MEN1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL20382395 | 0.82 | KMT2A (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |
| US-4965250-A | TETRAPEPTIDE; IMMUNE SYSTEM ACTIVATION | ADIR ET CIE (FR) | 1990-10-23 | — | — | US | disclosed |
| EP-0257602-A1 | (5R,6S,8R)-6-(1-hydroxyethyl)-2-(3R-pyrolidin-2-one-3-yl-)thiopenem-3-carboxylic acid | SCHERING CORPORATION (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4424343-A | Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products | BRISTOL MYERS COMPANY (US) | 1984-01-03 | — | — | US | disclosed |