Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.31 |
| ▸ | CYCS | P99999 | 3/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034718 | 0.91 | STAT3 (0.38) | STAT3STAT1TOP1SMAD3CYCS | |
| SCHEMBL10565770 | 0.90 | — | — | |
| SCHEMBL455575 | 0.80 | STAT3 (0.49) | STAT3STAT1TOP1CYCSDHODH | |
| SCHEMBL29727480 | 0.80 | STAT3 (0.49) | STAT3STAT1TOP1CYCSDHODH | |
| SCHEMBL351525 | 0.80 | BRD4 (0.35) | STAT3STAT1 | |
| SCHEMBL29763206 | 0.79 | STAT3 (0.48) | STAT3STAT1TOP1CYCSDHODH | |
| SCHEMBL28680348 | 0.79 | STAT3 (0.48) | STAT3STAT1TOP1CYCSDHODH | |
| SCHEMBL31678979 | 0.79 | STAT3 (0.48) | STAT3STAT1TOP1CYCSDHODH | |
| Phenol SCHEMBL27336875 | 0.78 | STAT3 (0.42) | STAT3STAT1 | |
| Hydrogen Peroxide SCHEMBL28310892 | 0.78 | STAT3 (0.43) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882234-A | TUMOR IMAGING AND PHOTODYNAMIC THERAPY AGENTS | HEALUX, INC. (US) | 1989-11-21 | — | — | US | claimed |
| EP-0539960-B1 | Hematoporphyrin derivatives complex salts and their use in the detection and treatment of neoplasms | WOJSKOWA AKAD TECH (PL) | 1997-03-05 | — | — | EP | disclosed |
| US-4882234-A | TUMOR IMAGING AND PHOTODYNAMIC THERAPY AGENTS | HEALUX, INC. (US) | 1989-11-21 | — | — | US | disclosed |
| US-4882234-A | TUMOR IMAGING AND PHOTODYNAMIC THERAPY AGENTS | HEALUX, INC. (US) | 1989-11-21 | — | — | US | disclosed |