SCHEMBL351525

SCHEMBL351525

CC(=O)c1c(C(C)=O)c2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 8/20 0.35
▸ MAPT P10636 3/20 0.34
▸ STAT3 P40763 1/20 0.34
▸ STAT1 P42224 1/20 0.34
▸ ALOX12 P18054 2/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ USP2 O75604 1/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ CSNK1A1 P48729 1/20 0.32
▸ CSNK1D P48730 1/20 0.32
▸ CLK2 P49760 1/20 0.32
▸ CSNK1G1 Q9HCP0 1/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ GAA P10253 2/20 0.31
▸ KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9234166 0.87 MEN1 (0.31) BRD4MAPTHSD17B10TDP1MEN1
Acetone SCHEMBL29186682 0.86 STAT3 (0.36) STAT3STAT1NPSR1HSD17B10ALDH1A1
SCHEMBL5034718 0.85 STAT3 (0.38) MAPTSTAT3STAT1HSD17B10ALDH1A1
SCHEMBL1597373 0.84 STAT3 (0.43) BRD4MAPTSTAT3STAT1ALOX12
SCHEMBL351897 0.83 STAT3 (0.45) BRD4MAPTSTAT3STAT1ALOX12
Acetic Acid SCHEMBL29181911 0.82 STAT3 (0.37) MAPTSTAT3STAT1ALOX12ALOX15
SCHEMBL351526 0.81 STAT3 (0.43) BRD4MAPTSTAT3STAT1ALOX12
Acetic Acid SCHEMBL28633839 0.81 STAT3 (0.33) STAT3STAT1
Acetic Acid SCHEMBL21121213 0.81 STAT3 (0.33) STAT3STAT1
Acetic Acid SCHEMBL29181913 0.81 STAT3 (0.33) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105464-A Single-component photovoltaic material based on porphyrin and fullerene, and preparation method and application thereof 华南理工大学 2021-07-13 — — CN claimed
CN-113105464-B Single-component photovoltaic material based on porphyrin and fullerene, and preparation method and application thereof 华南理工大学 2022-07-26 — — CN disclosed
CN-113105464-A Single-component photovoltaic material based on porphyrin and fullerene, and preparation method and application thereof 华南理工大学 2021-07-13 — — CN disclosed
US-8952357-B2 Cytochrome c552 color imaging element and method of manufacturing the same, cytochrome c552 photosensor and method of manufacturing the same, cytochrome c552 photoelectric transducer and method of manufacturing the same, and cytochrome c552 electronic device SONY CORPORATION (JP) 2015-02-10 — — US disclosed
CN-102318065-B Color imaging element and method for manufacturing the same, optical sensor and method for manufacturing the same, photoelectric transducer and method for manufacturing the same, and electronic device SONY CORP 2013-11-27 — — CN disclosed
CN-103367642-A Color imaging element and method of manufacturing the same, photosensor and method of manufacturing the same, and photoelectric transducer and method of manufacturing the same SONY CORP 2013-10-23 — — CN disclosed
CN-101866755-B Molecular device, imaging device, photosensor, and electronic apparatus SONY CORP 2012-09-26 — — CN disclosed
US-8178872-B2 Molecular device, imaging device, photosensor, and electronic apparatus SONY CORPORATION (JP) 2012-05-15 — — US disclosed
US-20120012823-A1 COLOR IMAGING ELEMENT AND METHOD OF MANUFACTURING THE SAME, PHOTOSENSOR AND METHOD OF MANUFACTURING THE SAME, PHOTOELECTRIC TRANSDUCER AND METHOD OF MANUFACTURING THE SAME, AND ELECTRONIC DEVICE SONY CORPORATION (JP) 2012-01-19 — — US disclosed
CN-102318065-A Color imaging element and method for manufacturing the same, optical sensor and method for manufacturing the same, photoelectric transducer and method for manufacturing the same, and electronic device SONY CORP 2012-01-11 — — CN disclosed
US-20100264409-A1 MOLECULAR DEVICE, IMAGING DEVICE, PHOTOSENSOR, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2010-10-21 — — US disclosed
CN-101866755-A Molecular device, image device, optical sensor and electronic equipment SONY CORP 2010-10-20 — — CN disclosed
US-20080283122-A1 Beta-Substituted Porphyrins CAMPBELL WAYNE MASON 2008-11-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080283122-A1 Beta-Substituted Porphyrins PPOX, HMBS, CRY1 BRD4 2431/4885MAPT 1304/4885STAT3 3336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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