Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 9/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909044 | 1.00 | P2RX1 (0.47) | P2RX1RENSIRT2 | |
| SCHEMBL8909763 | 0.90 | P2RX1 (0.44) | P2RX1RENSIRT2 | |
| SCHEMBL9800494 | 0.90 | P2RX1 (0.44) | P2RX1RENSIRT2 | |
| SCHEMBL8910517 | 0.89 | REN (0.55) | P2RX1REN | |
| SCHEMBL9800627 | 0.89 | REN (0.55) | P2RX1REN | |
| SCHEMBL9800675 | 0.88 | P2RX1 (0.50) | P2RX1RENSIRT2 | |
| SCHEMBL8909778 | 0.88 | P2RX1 (0.50) | P2RX1RENSIRT2 | |
| SCHEMBL9800541 | 0.85 | P2RX1 (0.51) | P2RX1RENSIRT2 | |
| SCHEMBL9800575 | 0.84 | REN (0.41) | P2RX1RENSIRT2 | |
| SCHEMBL9800460 | 0.84 | P2RX1 (0.52) | P2RX1RENSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |