Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518894 | 0.86 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5526539 | 0.86 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5518882 | 0.86 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6791764 | 0.85 | OPRD1 (1.00) | OPRD1OPRM1CYP1A2CYP3A4OPRK1 | |
| Hydrochloric Acid SCHEMBL6791215 | 0.85 | OPRD1 (0.71) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL5976396 | 0.84 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5975409 | 0.84 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5975405 | 0.84 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5528556 | 0.83 | OPRD1 (0.71) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5531105 | 0.83 | OPRD1 (0.71) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023466-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | ASTRA PHARMA INC. (CA) | 1997-07-03 | — | — | WO | claimed |