Ether

Ether

SCHEMBL8909531

CC(=O)O[Si](C)(C)C(C)(C)C.CCOCC

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475925 0.87 ALDH1A1 (0.33) ALDH1A1TSHRGAA
Ether SCHEMBL10423293 0.78 ALDH1A1 (0.44) ALDH1A1TSHRLMNAHSD17B10THRB
SCHEMBL16316919 0.72 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10THRB
Ether SCHEMBL10866831 0.71 ALDH1A1 (0.43) ALDH1A1TSHRLMNAHSD17B10THRB
SCHEMBL12540531 0.71 ALDH1A1 (0.33) ALDH1A1
SCHEMBL28558851 0.71 ALDH1A1 (0.37) ALDH1A1TSHRLMNAHSD17B10GAA
SCHEMBL839559 0.71
SCHEMBL1061431 0.69
SCHEMBL28706826 0.69
SCHEMBL28163566 0.69 MGAM (0.35) TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496160-B1 Synthetic conversion of bryostatin 2 into bryostatin 1 UNIV ARIZONA (US) 1997-05-07 EP claimed
EP-0496160-A1 Synthetic conversion of bryostatin 2 into bryostatin 1 ARIZONA BOARD OF REGENTS (US) 1992-07-29 EP claimed
EP-0496160-B1 Synthetic conversion of bryostatin 2 into bryostatin 1 UNIV ARIZONA (US) 1997-05-07 EP disclosed
EP-0496160-A1 Synthetic conversion of bryostatin 2 into bryostatin 1 ARIZONA BOARD OF REGENTS (US) 1992-07-29 EP disclosed