SCHEMBL890956

SCHEMBL890956

OCC(O)COc1ccc(Sc2ccc(OCC(O)CO)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.51
TSHR P16473 2/20 0.49
MAPK1 P28482 1/20 0.49
MAPT P10636 3/20 0.44
LMNA P02545 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
POLB P06746 1/20 0.44
CYP1A2 P05177 3/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 1/20 0.43
AGTR1 P30556 1/20 0.43
BACE1 P56817 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ATM Q13315 1/20 0.42
HTT P42858 1/20 0.42
CYP2C19 P33261 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14901493 0.92 AR (0.64) ARTSHRMAPK1MAPTLMNA
SCHEMBL26755845 0.89 AR (0.50) ARTSHRMAPK1MAPTLMNA
SCHEMBL6228324 0.88 AR (0.61) ARTSHRMAPK1MAPTLMNA
SCHEMBL13400539 0.85 BACE1 (0.50) ARTSHRMAPK1MAPTLMNA
SCHEMBL26756589 0.85 AR (0.44) ARTSHRMAPK1MAPTLMNA
SCHEMBL12516205 0.83 AR (0.54) ARTSHRMAPTLMNANPSR1
SCHEMBL14901594 0.83 MAPT (0.43) TSHRMAPK1MAPTLMNANPSR1
SCHEMBL14565150 0.83 MAPT (0.43) TSHRMAPTLMNANPSR1POLB
SCHEMBL14546451 0.83 LMNA (0.53) TSHRMAPTLMNANPSR1POLB
SCHEMBL8811629 0.82 AR (0.56) ARTSHRMAPK1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384870-B2 Method for setting polymerization condition and method for manufacturing optical material MITSUI CHEMICALS, INC. (JP) 2025-08-12 US disclosed
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US disclosed
EP-3308928-B1 METHOD FOR PRODUCING PLASTIC LENS AND USE OF A DEVICE FOR PRODUCING A PLASTIC LENS MITSUI CHEMICALS INC (JP) 2025-03-05 EP disclosed
EP-3521907-B1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
EP-3527597-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2024-08-07 EP disclosed
US-12054568-B2 Optical material composition and optical material TOKUYAMA CORPORATION (JP) 2024-08-06 US disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
CN-110869355-B Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition 株式会社德山 2023-11-14 CN disclosed
CN-112424260-B Photochromic compound and curable composition containing the same 株式会社德山 2023-10-13 CN disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed