Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22223496 | 0.85 | POLB (0.57) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL18205787 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL18205768 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL5674946 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL24704015 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL21182331 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL23000664 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL28214546 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL1202541 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL13044618 | 0.79 | PLK1 (0.55) | ALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659082-A | Nitro- and aminobenzamide compounds for neurodegenerative disorders | CENTAUR PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |