Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19746512 | 0.88 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL3316247 | 0.88 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL2747594 | 0.82 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL8740469 | 0.79 | MEN1 (0.36) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL9908423 | 0.76 | MEN1 (0.39) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL25233759 | 0.75 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL3332068 | 0.71 | — | — | |
| SCHEMBL3332078 | 0.71 | — | — | |
| SCHEMBL19604523 | 0.71 | — | — | |
| SCHEMBL5865804 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |