Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.31 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357967 | 0.96 | ALOX15 (0.56) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL78066 | 0.96 | ALOX15 (0.56) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11299586 | 0.96 | ALOX15 (0.56) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11298009 | 0.96 | ALOX15 (0.56) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11304480 | 0.96 | ALOX15 (0.56) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11309575 | 0.91 | ALOX15 (0.59) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| Undecane SCHEMBL28084006 | 0.90 | ALOX15 (0.63) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30681595 | 0.84 | ALOX15 (0.48) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8910117 | 0.83 | TP53 (0.48) | TP53ALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10602267 | 0.83 | TP53 (0.47) | TP53ALOX15CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597854-A | PHOTOGRAPHIC APPLICATIONS, COATINGS, BINDERS, POLYMERS, TRIAZINE OR PYRIMIDINE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0356687-B1 | Bis (tri-tertiary-alkylphenoxy) diphosphaspiroundecanes | GE SPECIALTY CHEM (US) | 1994-06-22 | — | — | EP | disclosed |
| EP-0523007-A1 | Novel tetramethylpiperidine compounds for use as stabilisers for organic materials | CIBA-GEIGY AG (CH) | 1993-01-13 | — | — | EP | disclosed |
| EP-0323408-A1 | 2-(2-Hydroxyphenyl)-benztriazole derivatives | CIBA-GEIGY AG (CH) | 1989-07-05 | — | — | EP | disclosed |
| US-4692532-A | STABILIZERS FOR ORGANIC MATERIALS | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |