Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 11/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910399 | 0.92 | GHSR (0.60) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL8910620 | 0.88 | GHSR (0.66) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL8908986 | 0.88 | GHSR (0.44) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL8909736 | 0.88 | GHSR (0.56) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7786014 | 0.88 | GHSR (0.68) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL8909790 | 0.88 | GHSR (0.43) | GHSRAGTR1XIAPNPY1R | |
| Trifluoroacetic Acid SCHEMBL9107682 | 0.84 | GHSR (0.63) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7791779 | 0.84 | GHSR (0.57) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL8909325 | 0.84 | GHSR (0.55) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL8909331 | 0.84 | GHSR (0.55) | GHSRAGTR1XIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016692-A1 | HETEROCYCLIC-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-06-22 | — | — | WO | claimed |
| US-5606054-A | Heterocyclic-fused lactams promote release of growth hormone | MERCK & CO., INC. (US) | 1997-02-25 | — | — | US | disclosed |