Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.85 |
| ▸ | ALPI | P09923 | 1/20 | 0.85 |
| ▸ | PKM | P14618 | 1/20 | 0.85 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.85 |
| ▸ | XIAP | P98170 | 1/20 | 0.85 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.61 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.61 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Phenylalanine SCHEMBL3486837 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL37367 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL2063249 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL9226754 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL6535507 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL6033327 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28229442 | 1.00 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL3057091 | 0.93 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28667668 | 0.93 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL17103846 | 0.93 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652136-A | ENZYME MUTANT WHERE CATALYTIC FUNCTIONALITY HAS BEEN MODIFIED OR REPLACED, MUTANT WILL HAVE PREFERENCE FOR SUBSTRATES SUPPLYING THE MODIFIED OR REPLACED CATALYTIC FUNCTIONAL GROUP | GENENCOR INTERNATIONAL, INC. (US) | 1997-07-29 | — | — | US | disclosed |
| US-5472855-A | Genetic engineering forming an enzyme mutants | GENENTECH, INC. (US) | 1995-12-05 | — | — | US | disclosed |
| US-5371008-A | Catalytically active enzyme-substrate complex comprising a subtilisin-related protease variant in contact with first substrate containing a first selected region | GENENCOR INTERNATIONAL, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5371190-A | Enzyme assisted catalysis | GENENCOR INTERNATIONAL, INC. (US) | 1994-12-06 | — | — | US | disclosed |