Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39477 | 0.95 | VCAM1 (0.56) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL27747905 | 0.95 | VCAM1 (0.56) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL27769174 | 0.95 | VCAM1 (0.56) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL7155322 | 0.95 | VCAM1 (0.56) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL11347714 | 0.95 | VCAM1 (0.56) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL27769201 | 0.95 | VCAM1 (0.56) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL5027033 | 0.93 | VCAM1 (0.55) | CA1CA2VCAM1KMT2ASMN1; SMN2 | |
| SCHEMBL28853602 | 0.89 | VCAM1 (0.54) | CA1CA2VCAM1KMT2APTGS2 | |
| SCHEMBL1577556 | 0.89 | VCAM1 (0.61) | CA1CA2VCAM1SMN1; SMN2MAPT | |
| SCHEMBL38445 | 0.87 | VCAM1 (0.60) | CA1CA2VCAM1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597854-A | PHOTOGRAPHIC APPLICATIONS, COATINGS, BINDERS, POLYMERS, TRIAZINE OR PYRIMIDINE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |