SCHEMBL891049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1979615	0.93	BRD4 (0.49)	KDM4EALDH1A1GAAMAPTHSD17B10
	SCHEMBL2246792	0.90	GAA (0.57)	KDM4EALDH1A1GAAMAPTHSD17B10
	SCHEMBL19020075	0.89	PTGER4 (0.48)	KDM4EALDH1A1GAAMAPTHDAC1
	SCHEMBL19058449	0.88	BRD4 (0.48)	KDM4EALDH1A1MAPTBRD4MALT1
	SCHEMBL16703087	0.85	CDK2 (0.46)	KDM4EALDH1A1GAAMAPTHSD17B10
	SCHEMBL891595	0.84	CA12 (0.44)	KDM4EALDH1A1GAAMAPTHDAC1
	SCHEMBL19058462	0.84	NQO2 (0.49)	HDAC1BRD4MALT1BCHEPDE3B
	SCHEMBL12094623	0.83	BRD4 (0.43)	KDM4EALDH1A1GAAMAPTHSD17B10
	SCHEMBL4951134	0.83	KDM4E (0.46)	KDM4EALDH1A1GAAMAPTHSD17B10
	SCHEMBL23286842	0.83	LNPEP (0.43)	KDM4EALDH1A1GAAMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.