Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003887 | 0.80 | SLC22A16 (0.31) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL338774 | 0.80 | MEN1 (0.36) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| SCHEMBL30673761 | 0.75 | MAPT (0.44) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL30673768 | 0.75 | MAPT (0.44) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL5190821 | 0.75 | MAPT (0.44) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL31173704 | 0.75 | MAPT (0.44) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL8911564 | 0.75 | SLC22A16 (0.38) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| SCHEMBL737340 | 0.73 | CPT2 (0.38) | LAP3MAPTSLC22A16TSHRCHRM2 | |
| SCHEMBL2553127 | 0.73 | SLC22A16 (0.32) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| SCHEMBL11347712 | 0.73 | SLC22A16 (0.32) | MAPTSLC22A16TSHRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591882-A | Process for preparing organophosphates useful for increasing the ocular haemo- and biocompatibility of synthetic polymers | BIOCOMPATIBLES LIMITED (GB) | 1997-01-07 | — | — | US | disclosed |
| EP-0518959-B1 | METHOD OF IMPROVING THE OCULAR HAEMO AND BIOCOMPATIBILITY OF SYNTHETIC POLYMERS | BIOCOMPATIBLES LTD (GB) | 1996-11-20 | — | — | EP | disclosed |
| US-5422402-A | Surface treatment (of an acrylic, polypropylene, polyethylene, polyurethane, polysaccharide, or cellulosic material) with quaternary ammonium phosphate inner salt having a reactive functional group; contact lenses; blood filtration | BIOCOMPATIBLES LIMITED (GB) | 1995-06-06 | — | — | US | disclosed |
| EP-0518959-A1 | METHOD OF IMPROVING THE OCULAR HAEMO AND BIOCOMPATIBILITY OF SYNTHETIC POLYMERS. | BIOCOMPATIBLES LTD (GB) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013639-A1 | METHOD OF IMPROVING THE OCULAR HAEMO AND BIOCOMPATIBILITY OF SYNTHETIC POLYMERS | BIOCOMPATIBLES LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |