SCHEMBL8910873

SCHEMBL8910873

CCCCS(=O)(=O)N(C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HIF1A Q16665 1/20 0.43
EPAS1 Q99814 1/20 0.43
ESR1 P03372 2/20 0.42
CA2 P00918 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CNR2 P34972 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.37
NPC1 O15118 1/20 0.37
JAK2 O60674 1/20 0.37
RAB9A P51151 1/20 0.37
PAX8 Q06710 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5345859 0.89 CA12 (0.46) CA12CA9TDP1HIF1AEPAS1
SCHEMBL13762630 0.86 CA12 (0.50) CA12CA9TDP1ESR1CA2
SCHEMBL15672856 0.86 CA12 (0.50) CA12CA9CA2HSP90AA1MCOLN3
SCHEMBL12352208 0.83 CNR2 (0.47) ESR1CA2CNR2MCOLN3KDM4E
SCHEMBL6301951 0.82 ESR1 (0.44) HIF1AESR1CNR2ALDH1A1MAPK1
SCHEMBL5393886 0.81 CA12 (0.40) CA12CA9CA2HSP90AA1MCOLN3
SCHEMBL7179930 0.80 HSD17B1 (0.51) ESR1CNR2ALDH1A1
SCHEMBL3766593 0.79 CA12 (0.44) CA12CA9CA2HSP90AA1MCOLN3
SCHEMBL15672926 0.78 CA12 (0.50) CA12CA9CA2HSP90AA1MCOLN3
Hydrochloric Acid SCHEMBL21633659 0.78 CA12 (0.43) CA12CA9CA2HSP90AA1MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995032500-A1 SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA THE DOW CHEMICAL COMPANY (US) 1995-11-30 WO claimed
US-7244300-B2 Inkjet recording ink FUJIFILM CORPORATION (JP) 2007-07-17 US disclosed
US-5591503-A Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant THE DOW CHEMICAL COMPANY (US) 1997-01-07 US disclosed
WO-1995032500-A1 SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA THE DOW CHEMICAL COMPANY (US) 1995-11-30 WO disclosed