Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Butanediol SCHEMBL8910988 | 0.94 | TSHR (0.39) | TSHRSHBGSMN1; SMN2LMNAALDH1A1 | |
| 1,6-Hexanediol SCHEMBL27420700 | 0.88 | TSHR (0.40) | TSHRSHBGSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8508682 | 0.88 | TSHR (0.40) | TSHRSHBGSMN1; SMN2LMNAALDH1A1 | |
| Ethylene Glycol SCHEMBL23716760 | 0.84 | TSHR (0.47) | TSHRSHBG | |
| 1,4-Butanediol SCHEMBL2786325 | 0.77 | TSHR (0.50) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| Cyclohexanol SCHEMBL21925166 | 0.77 | TSHR (0.59) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL4814734 | 0.76 | SIGMAR1 (0.33) | TSHRSHBGLMNA | |
| 1,6-Hexanediol SCHEMBL5070773 | 0.73 | TSHR (0.50) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| 1,4-Butanediol SCHEMBL10422739 | 0.73 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| 1,4-Butanediol SCHEMBL13518103 | 0.73 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681655-A | MODIFIED AROMATIC POLYESTER | SINCO ENGINEERING S.P.A. (IT) | 1997-10-28 | — | — | US | disclosed |
| EP-0697040-A1 | FIBRES WITH HIGH ELASTIC MODULUS FROM POLYESTER RESINS | SINCO ENGINEERING S.P.A. (IT) | 1996-02-21 | — | — | EP | disclosed |
| WO-1994026961-A1 | FIBRES WITH HIGH ELASTIC MODULUS FROM POLYESTER RESINS | M.& G. RICERCHE S.P.A. (IT) | 1994-11-24 | — | — | WO | disclosed |