Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800522 | 0.81 | MEN1 (0.43) | SYKIDO1MEN1KMT2ACKS1B | |
| SCHEMBL30841403 | 0.81 | SYK (0.47) | SYKKLK7KLK5IDO1MEN1 | |
| SCHEMBL30841401 | 0.80 | SYK (0.48) | SYKKLK5IDO1MEN1KMT2A | |
| SCHEMBL12189898 | 0.80 | SYK (0.53) | SYKIDO1MEN1KMT2AMAPT | |
| SCHEMBL29171354 | 0.80 | SYK (0.47) | SYKIDO1MEN1KMT2AMAPT | |
| SCHEMBL30841405 | 0.79 | SYK (0.45) | SYKKLK7KLK5IDO1MEN1 | |
| SCHEMBL2525899 | 0.79 | SYK (0.47) | SYKIDO1MEN1KMT2AMAPT | |
| SCHEMBL8908668 | 0.78 | SYK (0.53) | SYKKLK7KLK5IDO1MEN1 | |
| SCHEMBL14280788 | 0.78 | SYK (0.48) | SYKIDO1MAPTL3MBTL1TPSAB1 | |
| SCHEMBL30841384 | 0.77 | SYK (0.45) | SYKKLK7KLK5IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |