Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911004 | 0.81 | SYK (0.47) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL27816443 | 0.81 | MEN1 (0.49) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL27795533 | 0.81 | MEN1 (0.49) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL15641611 | 0.81 | MEN1 (0.46) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL15641585 | 0.79 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL15641590 | 0.79 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CA12 | |
| Acetic Acid SCHEMBL4858065 | 0.77 | MEN1 (0.42) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL15641614 | 0.76 | MEN1 (0.47) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL14043519 | 0.75 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL28686971 | 0.74 | HDAC6 (0.33) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |