Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911997 | 0.90 | HTT (0.38) | HTTUSP2ALOX15TSHRNPSR1 | |
| SCHEMBL9194094 | 0.83 | STAT3 (0.38) | LMNACYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9191254 | 0.83 | STAT3 (0.38) | LMNACYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL7153072 | 0.83 | STAT3 (0.38) | LMNACYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL8911992 | 0.79 | STAT3 (0.40) | HTTUSP2ALOX15TSHRNPSR1 | |
| SCHEMBL9019756 | 0.78 | PRKCA (0.53) | LMNAPRKCAALDH1A1TDP1AR | |
| SCHEMBL7386406 | 0.77 | HTT (0.46) | HTTUSP2ALOX15TSHRNPSR1 | |
| SCHEMBL28173887 | 0.76 | STAT3 (0.47) | LMNACYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL13752124 | 0.75 | KMT2A (0.38) | HTTUSP2ALOX15TSHRNPSR1 | |
| SCHEMBL8423991 | 0.75 | STAT3 (0.44) | LMNAGAAMAPK1STAT3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35558-E | (2R)-2-[di(2-propyl)phosphonyylmethoxy]-3-P-toluenesulfonyloxy-1-trimethylacetoxypropane, its preparation and use | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1997-07-08 | — | — | US | claimed |
| US-5130427-A | Viricides formed by etherification, esterification and reaction with a phosphonate containing compound | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-07-14 | — | — | US | claimed |
| EP-0470809-A1 | Antiviral nucleosides, compounds useful in their preparation and processes of making them | Ceskoslovenska akademie ved (CS) | 1992-02-12 | — | — | EP | claimed |
| US-RE35558-E | (2R)-2-[di(2-propyl)phosphonyylmethoxy]-3-P-toluenesulfonyloxy-1-trimethylacetoxypropane, its preparation and use | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1997-07-08 | — | — | US | disclosed |
| US-5130427-A | Viricides formed by etherification, esterification and reaction with a phosphonate containing compound | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-07-14 | — | — | US | disclosed |
| EP-0470809-A1 | Antiviral nucleosides, compounds useful in their preparation and processes of making them | Ceskoslovenska akademie ved (CS) | 1992-02-12 | — | — | EP | disclosed |