Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 2/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911175 | 0.83 | ADORA2A (0.31) | — | |
| SCHEMBL8910616 | 0.82 | CYP3A4 (0.51) | FGFR1SLC22A6CYP3A4TYMPHPRT1 | |
| SCHEMBL29437221 | 0.71 | CYP3A4 (0.73) | FGFR1SLC22A6CYP3A4HPRT1 | |
| SCHEMBL385752 | 0.71 | CYP3A4 (0.73) | FGFR1SLC22A6CYP3A4HPRT1 | |
| SCHEMBL66563 | 0.71 | CYP3A4 (0.73) | FGFR1SLC22A6CYP3A4HPRT1 | |
| SCHEMBL8418890 | 0.69 | ADORA2A (0.61) | FGFR1SLC22A6CYP3A4HPRT1 | |
| SCHEMBL1095677 | 0.67 | FGFR1 (0.63) | FGFR1SLC22A6CYP3A4TYMPHPRT1 | |
| SCHEMBL1095680 | 0.67 | FGFR1 (0.63) | FGFR1SLC22A6CYP3A4TYMPHPRT1 | |
| SCHEMBL2931575 | 0.67 | FGFR1 (0.51) | FGFR1SLC22A6CYP3A4TYMPHPRT1 | |
| SCHEMBL7267515 | 0.67 | CYP3A4 (0.67) | FGFR1SLC22A6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35558-E | (2R)-2-[di(2-propyl)phosphonyylmethoxy]-3-P-toluenesulfonyloxy-1-trimethylacetoxypropane, its preparation and use | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1997-07-08 | — | — | US | disclosed |
| US-5130427-A | Viricides formed by etherification, esterification and reaction with a phosphonate containing compound | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-07-14 | — | — | US | disclosed |
| EP-0470809-A1 | Antiviral nucleosides, compounds useful in their preparation and processes of making them | Ceskoslovenska akademie ved (CS) | 1992-02-12 | — | — | EP | disclosed |