Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911647 | 1.00 | TRPV1 (0.59) | TRPV1CA1CA2MMP1MMP2 | |
| SCHEMBL9239964 | 1.00 | TRPV1 (0.59) | TRPV1CA1CA2MMP1MMP2 | |
| SCHEMBL3277623 | 0.94 | TRPV1 (0.58) | TRPV1CA1CA2MMP1MMP2 | |
| SCHEMBL10628669 | 0.84 | CA1 (0.52) | TRPV1CA1CA2MMP1MMP2 | |
| SCHEMBL9277499 | 0.83 | ALDH1A1 (0.51) | TRPV1CA1CA2MMP2MMP9 | |
| SCHEMBL13753685 | 0.83 | CA1 (0.64) | TRPV1CA1CA2MMP1MMP2 | |
| SCHEMBL15199080 | 0.82 | ALDH1A1 (0.56) | TRPV1LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL10630564 | 0.82 | CA1 (0.52) | TRPV1CA1CA2MMP1MMP2 | |
| SCHEMBL31014206 | 0.81 | CA1 (0.57) | CA1CA2MMP1LMNAMAPK1 | |
| SCHEMBL11704757 | 0.80 | KMT2A (0.73) | LMNAMAPK1HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591503-A | Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant | THE DOW CHEMICAL COMPANY (US) | 1997-01-07 | — | — | US | claimed |
| WO-1995032500-A1 | SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA | THE DOW CHEMICAL COMPANY (US) | 1995-11-30 | — | — | WO | claimed |
| US-5591503-A | Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant | THE DOW CHEMICAL COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1995032500-A1 | SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA | THE DOW CHEMICAL COMPANY (US) | 1995-11-30 | — | — | WO | disclosed |