Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10426873 | 0.72 | MAPT (0.33) | ALDH1A1MAPT | |
| SCHEMBL16196731 | 0.69 | MKNK1 (0.31) | — | |
| SCHEMBL3743227 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4456405 | 0.68 | MAPT (0.37) | MAPT | |
| SCHEMBL756061 | 0.65 | PREP (0.33) | — | |
| SCHEMBL22722363 | 0.65 | — | — | |
| SCHEMBL8984541 | 0.64 | MKNK1 (0.39) | — | |
| SCHEMBL18807873 | 0.62 | AKT1 (0.32) | MAPTKMT2A | |
| SCHEMBL18807726 | 0.62 | AKT1 (0.32) | MAPTKMT2A | |
| SCHEMBL18807722 | 0.62 | AKT1 (0.32) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |