Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178814 | 0.86 | HDAC1 (0.52) | HDAC6SMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL14368851 | 0.86 | NPC1 (0.55) | HDAC6SMN1; SMN2HPGDNPSR1ALDH1A1 | |
| Phosphoric Acid SCHEMBL7716499 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2HPGDNPSR1ALDH1A1NPC1 | |
| SCHEMBL15856847 | 0.81 | LMNA (0.43) | HDAC6SMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL16693227 | 0.80 | LMNA (0.50) | HDAC6SMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL21246818 | 0.80 | NPC1 (0.56) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8910837 | 0.80 | GAA (0.51) | SMN1; SMN2NPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL15853473 | 0.80 | TAAR1 (0.42) | ALDH1A1NPC1RAB9APOLBLMNA | |
| SCHEMBL16693290 | 0.79 | HDAC3 (0.49) | SMN1; SMN2HPGDNPSR1ALDH1A1NPC1 | |
| SCHEMBL8016168 | 0.79 | KMT2A (0.53) | SMN1; SMN2HPGDNPSR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609970-A | GENERATING ELECTROMAGNETIC RADIATION | POLAROID CORPORATION (US) | 1997-03-11 | — | — | US | claimed |
| US-5609970-A | GENERATING ELECTROMAGNETIC RADIATION | POLAROID CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |