SCHEMBL8911306

SCHEMBL8911306

OC1(c2ccccc2)C=CC=CC1c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.32
MAOA P21397 6/20 0.32
MAOB P27338 6/20 0.32
PTGS2 P35354 1/20 0.31
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28914096 0.90 KDM1A (0.33) KDM1AMAOB
SCHEMBL365626 0.79 CHRNA7 (0.32) CHRNA7
SCHEMBL17707789 0.77 AKR1C1 (0.33) KDM1AMAOAMAOB
SCHEMBL7546042 0.77 P2RX1 (0.32)
SCHEMBL23203046 0.76 CHRNA7 (0.31) KDM1ACHRNA7
SCHEMBL9100196 0.76 KDM1A (0.34) KDM1AMAOAMAOBCHRNA7
SCHEMBL10445207 0.76 MAOB (0.35) MAOAMAOB
SCHEMBL28088570 0.76 HSD11B1 (0.31)
SCHEMBL9751875 0.74 KDM1A (0.32) KDM1AMAOAMAOB
SCHEMBL28723673 0.74 KDM1A (0.32) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255957-A Catechol-based phenolic amine curing agent and preparation method thereof 江苏三吉利化工股份有限公司 2024-06-28 CN disclosed
CN-1579999-A Preparation of multi-photon nano composite membrane self-cleaning (antibacterial) ceramic by combined technique UNIV BEIJING CHEMICAL (CN) 2005-02-16 CN disclosed
CN-1552653-A Self-cleaning glass of nanometer composite membrane with multifunctional two-photon 北京化工大学 2004-12-08 CN disclosed
EP-0712493-A4 A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY SPHINX PHARMA CORP (US) 1997-01-15 EP disclosed
EP-0712493-A1 A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY SPHINX PHARMACEUTICALS CORPORATION (US) 1996-05-22 EP disclosed
WO-1995004277-A1 A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY SPHINX PHARMACEUTICALS CORPORATION (US) 1995-02-09 WO disclosed
US-5063134-A Silicon-containing novolaks for multilayer photoresists developed by an aqueous alkaline solution; oxygen-plasma resistance; resolution KABUSHIKI KAISHA TOSHIBA (JP) 1991-11-05 US disclosed