SCHEMBL8911405

SCHEMBL8911405

CCOC(=O)CC1(O)CCCC(C=CC(CCCCCCCCCC(Oc2ccccc2)O[SiH](C)C)C(C)(C)C)C1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LTB4R Q15722 18/20 0.46
▸ LTB4R2 Q9NPC1 12/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8909237 0.95 LTB4R (0.44) LTB4RLTB4R2
SCHEMBL9051549 0.92 LTB4R (0.52) LTB4RLTB4R2
SCHEMBL8909946 0.86 LTB4R (0.45) LTB4RLTB4R2
SCHEMBL9051369 0.86 LTB4R (0.50) LTB4RLTB4R2
SCHEMBL8909293 0.82 LTB4R (0.45) LTB4RLTB4R2
SCHEMBL8909986 0.82 LTB4R (0.45) LTB4RLTB4R2
SCHEMBL8909963 0.77 LTB4R (0.51) LTB4RLTB4R2
SCHEMBL9048895 0.77 LTB4R (0.51) LTB4RLTB4R2
SCHEMBL8910647 0.77 LTB4R (0.62) LTB4RLTB4R2
SCHEMBL8910643 0.77 LTB4R (0.62) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639902-A FOR TREATING PSORIASIS ADIR ET COMPAGNIE (FR) 1997-06-17 — — US disclosed
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